About human placenta extract (placenta)

About human placenta extract (placenta)
About human placenta extract (placenta)
Free medical treatment (not covered by insurance)
Aging care, recovery from fatigue, autonomic nervous system, approach to beautiful skin
Unapproved drugs, etc. (use for different purposes)
Placenta has been approved under the Pharmaceuticals and Medical Devices Act for its efficacy and effects, such as improving liver function in chronic liver disease and improving menopausal disorders. However, it is not approved in Japan because the evidence has not been established.
Pharmaceuticals with the generic name of human placenta extract (placenta) are approved in Japan, but the approved efficacy, effect, dosage and administration are different from the purpose and method of use at our hospital.
Although there have been no reports of significant risk or slow virus infection from placenta injections over the past 60 years, the theoretical risk of transmission of vCJD (variant Creutzfeldt-Jakob disease) cannot be ruled out.
*In our hospital, we explain all the information such as efficacy, risk, content ingredients, storage method, etc.
  • “Explanation to patients” In using this drug, in addition to the necessity of this drug in the treatment of diseases, safety measures have been taken to prevent the spread of infectious diseases during the manufacture of this drug. Efforts should be made to explain to the patient that the risk of infectious disease transmission due to the use of the placenta as a raw material cannot be completely eliminated, and to obtain their understanding.
  • (1) This drug is screened for viral and bacterial infections by interviewing the raw material provider about travel history, etc., and serological tests. have undergone nucleic acid amplification testing (NAT), and matched domestic human placentas are used for manufacturing.However, there is always the possibility that viruses below the detection limit of the NAT are mixed.This drug is manufactured by the hydrochloric acid hydrolysis method, and in the manufacturing process for the purpose of virus inactivation, hydrochloric acid heat treatment at 1 ° C or higher for 101 hour or longer and high pressure steam sterilization at 1 ° C for 121 minutes are performed. However, since the possibility of infection due to the use of human placenta cannot be completely ruled out, it is recommended that careful observation be made before use.

    (2) To date, there have been no reports of the transmission of variant Creutzfeldt-Jakob disease (vCJD) due to the administration of this drug. , Patients should be fully informed of its use, and the need for treatment should be carefully considered before use.
Overview of occurrence of side effects, etc.
“Of the 98 cases surveyed, 19 (19.4%) had some kind of side effect, and the main one was redness and pain at the injection site in 7 cases, which accounted for 7.1% of all cases. 36,8%.In addition, no clinically significant changes were observed in laboratory test values. 1) 2) (at the end of re-evaluation)”
Serious side effects
Since shock may occur, administration should be discontinued and appropriate measures should be taken if such symptoms occur.
Other side effects
If any of the following side effects occur, appropriate measures should be taken according to the symptoms.
Table of other side effects
5% or more 0.1 to less than 5%
Hypersensitivity Chills, nausea, fever, redness, rash, etc.
injection site Pain, redness, etc.
Note) If such symptoms occur, administration should be discontinued.
Route of administration
This drug should only be used for subcutaneous injection.
When cutting ampoule
This product uses a "one-point cut ampoule", so after wiping the cut part with ethanol cotton, etc., break it off in the opposite direction of the mark on the branch of the ampoule without using a file.
lactation deficiency
Although the mechanism of action of melsumon is not yet fully clarified, it has been recognized that it promotes cell respiration, promotes wound healing, and has anti-fatigue effects. It is presumed to have an activating action, increase the metabolism of tissue cells, and normalize the abnormal state of the body.
Promotes tissue respiration
As a result of measuring the effect of Melsmon on rat liver tissue respiration by the Warburg method, Melsmon was found to promote respiration about 5.7 times as much as physiological saline.
Promotes wound healing
In experimental burn wounds using rats, Melsumon showed a wound healing-promoting effect compared to controls.
anti-fatigue effect
Melsumon was found to have anti-fatigue properties in an underwater swimming fatigue test using mice.
Vitreous and subconjunctival hemorrhage absorption promotion
Experimental hemorrhage was induced in the vitreous body and under the bulbar conjunctiva of the rabbit eyeball, and as a result of observing its absorption promoting effect, Melsumon showed a hemorrhagic absorption promoting effect compared to the control.
Although this drug contains various trace ingredients derived from human placenta, specific substances cannot be indicated as active ingredients.
The components currently quantified are as follows.
amino acid Lysine, alanine, aspartic acid, leucine, glutamic acid, glycine, valine, serine, tyrosine, phenylalanine, threonine, arginine, proline, isoleucine, methionine, histidine
Record keeping
Since this drug is a specified biological product, when using this drug, record the name of the drug, its serial number, the date of use, the name and address of the patient who used it, and store it for at least 20 years. matter.
Regarding risks and side effects
  • ▷ Pain and redness during injection
  • ▷Scratch after injection
  • ▷ Post-injection subcutaneous bleeding, internal bleeding
*You may not be able to donate blood after the injection.

Daily life after injection
  • ▷ Bathing on the same day is possible
  • ▷ Sports on the day are possible
  • ▷Vaccination on the day is possible
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1 ampoule 3,000
*The unit is ¥.
*The initial consultation fee is ¥3,000 (¥3,300).
* From 2 ampoule.
*Treatment is free medical treatment (not covered by insurance).

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