A certain cosmetic surgeon administered exosomes, stem cell culture supernatant, intravenously to a top athlete and world champion professional boxer, and the case was heavily promoted in a press release and on YouTube.

This is an outrageous medical procedure and would never be tolerated in the sports world.

Complete doping.

Doping has recently come under strict scrutiny even in professional boxing.

I have been involved in professional boxing for 25 years as a professional boxing trainer, and as a fellow cosmetic surgeon I believe this is a major event.

Why doping?

1. The intravenous administration of unnecessary drugs to speed up recovery or improve physical performance.

2: Exosomes containing growth factors that are clearly prohibited from administration and are on the negative list are being administered.

3: Administration of unauthorized substances is not permitted.

It is impossible to administer pure exosomes, as they become contaminated with various cytokines, including growth factors, during the manufacturing process.

Also, there are no cosmetic surgeons who can clearly tell us the specific ingredients and their amounts. (If there are, I would like to know.)

The professional boxer probably didn't know about doping because he didn't have any knowledge about it. This cosmetic surgeon's outrageous act is so outrageous that it could wipe out the career of a professional boxing world champion.

Athletes should never receive stem cell culture supernatant or exosome infusions.

This is outright doping.

WADA 2025 Prohibited Substances and Methods List

https://www.wada-ama.org/en/resources/2025-prohibited-list

There has been a lot of ethics surrounding cosmetic surgeons being highlighted in recent posts made inappropriately in an attempt to look good on Instagram, but isn't this also a big problem?

　The dark side of regenerative medicine, with its high incidence of accidents: "Doctors who prioritize profits are selling them like crazy"

Reading Time: <1 minute

"Exosomes" have recently become popular in the cosmetic medicine industry. Treatments that use this substance released from cells are sometimes considered "regenerative medicine," and celebrities and famous businessmen have been promoting it. However, behind the hype of "a new era of cosmetic medicine," there is a big pitfall. [See photos] The rapid increase in regenerative medicine clinics in Ginza and elsewhere 　***

　Ginza and Nihonbashi in Tokyo are high-end shopping districts that represent Japan. Clinics advertising regenerative medicine have been increasing in number in these areas in recent years. The Ministry of Health, Labor and Welfare issued an emergency order to one such clinic in October last year, suspending the provision of regenerative medicine. A reporter from a national newspaper said, "The clinic that received the emergency order was a clinic that provides regenerative medicine, which claims to prevent cancer, as an optional treatment. The clinic provided a treatment in which immune cells called NK cells were taken from the patient's body, cultured and processed, and then returned to the body to activate the patient's immune system, but two of the patients who received the treatment ended up with a serious infection." This treatment is extremely expensive, costing around 10 million yen per course. The selling point was that the safety was guaranteed because the cells were cultured in a "clean room" in a dedicated facility. "However, the processed cells cultured there were contaminated with bacteria, so in the end it must have been poor management. The medical corporation that operated the clinic promptly closed the clinic, but another affiliated clinic continues to operate as if nothing had happened." (ibid.)

A never-ending stream of medical accidents

When you hear the term "regenerative medicine," many people will surely conjure up images of "advanced medical care" or "cutting-edge medical care." Some may recall the "iPS cells" of Shinya Yamanaka, winner of the Nobel Prize in Physiology or Medicine in 2012, or may conjure up the dream story of "immortality and longevity." However, when asked "Is it safe?", most people probably have no idea. In fact, in recent years, there has been a never-ending stream of troubles and medical accidents surrounding regenerative medicine. It seems that regenerative medicine, which has been overemphasized in its "infinite possibilities" and has neglected its safety, is becoming rampant. What on earth is happening in the field of regenerative medicine?

"It's like regenerative medicine"

　In the world of regenerative medicine, which is a mixture of good and bad, the term "regenerative medicine" itself is vague and unclear, points out Nobuyuki Kazuki, representative director of the Regenerative Medicine Safety Promotion Organization. "As you may imagine, regenerative medicine is a treatment that "regenerates" cells, tissues, and organs damaged by disease or injury back to normal. However, there are two types of regenerative medicine that are generally provided today: regenerative medicine provided within the law, and "quasi-regenerative medicine" provided outside the law." (Kazuki) The "law" here refers to the Act on Ensuring the Safety of Regenerative Medicine, etc. (Act on Ensuring the Safety of Regenerative Medicine, etc.), which was enacted in 13 and came into effect the following year. In regenerative medicine, in many cases, cells are taken from the patient's body, cultured and processed, and then returned to the patient's body for treatment. The Act on Ensuring the Safety of Regenerative Medicine stipulates strict processes that must be followed when performing such regenerative medicine. "Specifically, when providing regenerative medicine, medical institutions are required to create a 'Regenerative Medicine Provision Plan' for each treatment method for each disease. Then, these provision plans are submitted to the 'Specific Certified Regenerative Medicine Committee', which has been certified by the Ministry of Health, Labor and Welfare based on the Safety and Security Act. After approval, clinics can only provide regenerative medicine after submitting a notification to the Minister of Health, Labor and Welfare." (ibid.)

The law is "watered down"

　However, even if the Safety Assurance Act sets out strict rules, if the clinic does not actually follow them, the safety will naturally end up being nothing more than a pipe dream. The clinic introduced at the beginning is a prime example of this problem. According to the national newspaper reporter mentioned above, "The clinic that received the emergency order in October also created a provision plan based on the Safety Assurance Act and obtained the committee's approval. Furthermore, the medical corporation that runs this clinic apparently entrusted the operation of its own cultivation center to a bio-company listed on the Tokyo Stock Exchange Growth Market. However, an on-site inspection by the Ministry of Health, Labor and Welfare after the emergency order confirmed multiple violations of the law, including provision in a way that differed from the plan, leading to the issuance of an improvement order. It is by no means possible to say that "it is safe just because the committee has approved it." In other words, the Safety Assurance Act has been effectively gutted, and it is almost impossible for ordinary patients to tell which regenerative medicine is truly safe.

Selling nonstop with a focus on profit

　Even regenerative medicine provided within the law has questionable safety, so you can imagine how unsafe "as if regenerative medicine" provided outside the law is... However, in the current regenerative medicine industry, this "as if regenerative medicine" is extremely popular. Kazuki sighs. "The most representative of this type of 'regenerative medicine' is a treatment called exosome therapy or stem cell culture supernatant therapy. These do not use cultured stem cells directly, but rather extract the supernatant fluid remaining after culture, or a substance called exosomes secreted by the cells, and apply it to the skin or inject it into the muscle to achieve a therapeutic effect. Since the cells are not injected into the body, it is outside the jurisdiction of the Safety and Security Act, and there is no need to create a troublesome donation plan or apply for deliberation at a committee. Since it uses the so-called 'waste' after culturing cells, the price is only a few tens of thousands of yen, which is incomparably cheaper than regenerative medicine provided within the law. Moreover, it is popular because it is 'easy', so doctors who do not understand the effects or risks are selling it with 'profit first' in mind."

There is also a risk of risk to life

　In fact, when searching for supernatant fluid and exosomes on the Internet, you will find many claims of dreamlike effects such as anti-aging, repairing damaged tissue, hair growth, fatigue recovery, and immune regulation. Some of these claims even claim to be cutting-edge medical treatments, such as "using iPS cells." However, in reality, there are many inferior products on the market that are far from being "dreamlike treatments," and it cannot be denied that they may even put your life at risk. "One of the risks of 'regenerative medicine' is that you don't know who's cells are the raw material for the product. In regenerative medicine within the scope of the law, basically, the cells used are one's own cells. However, according to our research, of the approximately 700 medical facilities currently offering supernatant fluid therapy or exosome therapy in Japan, very few facilities clearly announce that they use the patient's own cells. In fact, more than 8% are derived from other people's cells, or worse, they may not even be derived from human cells. In addition, expert research has revealed malicious cases in which a 'mysterious liquid' that claims to be exosomes but does not contain any exosomes at all is used, so caution is required."

"Suicidal"

　Smearing a mysterious liquid of unknown origin onto the skin - the very thought of it is terrifying, but what's even more dangerous is the fact that there is a treatment option in which the liquid is injected intravenously. By "intravenous injection", the active ingredients in the supernatant and exosomes circulate throughout the body more effectively, and are more effective against a variety of diseases. That's the selling point, but experts say it's nothing less than a "suicidal act" that could end in death at any time. In fact, the Regenerative Medicine Consultation Room of the Japan Regenerative Medicine Safety Promotion Organization receives desperate "cries" every day. Kazuki says: "A man who had erectile dysfunction due to psychotropic drugs received a local injection of exosomes into his penis at a clinic. A few days later, he began to experience severe pain and numbness in his limbs, making it difficult for him to even sit up. When he sought medical advice at a clinic, he was turned away, with the explanation that it was a 'mental problem.' Another man was recommended an exosome infusion by a hospital to treat a cerebral infarction. He paid a total of 10 million yen for 400 infusion treatments, but by the time the ninth infusion had finished, there was no effect at all. When he asked the doctor for an explanation, he was simply evaded."

Decreased level of consciousness and emergency transport

　A doctor who runs a regenerative medicine clinic in Tokyo also testifies: "Applying supernatant fluid or exosomes to the skin as a beauty serum poses almost no risk in terms of health damage, and in fact has been shown to have some beneficial aspects. However, this is only possible if the serum does not penetrate deeper than the dermis. If there are impurities in the supernatant fluid or exosomes, injecting them into a vein will cause the impurities to circulate throughout the body and, in the worst case scenario, can even be fatal. A doctor I know was suggested by a company to offer intravenous exosome injections as a treatment at his hospital, and when he tried injecting them into the veins of his own arm, his consciousness immediately dropped. He ended up having to be rushed to the hospital." Nevertheless, he says that the reason why the dangerous practice of "intravenous injection" is so prevalent is solely due to doctors' ignorance, and "Among the doctors who offer what appears to be regenerative medicine, there are quite a few who are not specialists in regenerative medicine. The reason they are using supernatant fluid and exosomes is simply because they have been persuaded by unscrupulous cell dealers who tell them that it will be profitable. Anyone can produce supernatant fluid and exosomes as long as they have the necessary machinery, and no qualifications are required, so recently many businessmen have been getting into the cell culture business with a "venture mentality." These fledgling businesses are approaching doctors who are not specialists by asking, "Would you like to work with exosomes?" (ibid.) Until now, the world of regenerative medicine has only focused on its positive aspects. It would be great if research could advance and eliminate "incurable diseases," but it should be remembered that there are still many pitfalls lurking behind the claims of "immortality and longevity." Article published in the January 2025, 1 issue of "Weekly Shincho"

The reality of illegal beauty salons

Reading Time: <1 minuteIn Nagoya, illegal beauty salons are left unchecked even if they repeatedly promote themselves in violation of the Pharmaceutical and Medical Device Act, the Act against Unjustifiable Premiums and Misleading Representations, and the Medical Practitioners Act, because they are not arrested by the police authorities. A cosmetic surgeon engaged in inappropriate behavior during an autopsy on a donated body, causing the biggest uproar in the history of the cosmetic surgery industry, and has been heavily criticized by people in various fields, including the medical community. It is ethically unacceptable, and has caused great damage to the medical community and developed into a social problem, but it is not a criminal act. The doctor's lack of morals and failure to properly apologize for his actions, and the doctor's employer's incorrect initial response have caused the uproar to expand, lowering the image of cosmetic surgeons. It was a very sad incident. Even if an aesthetician acts in a morally unjust manner, due to their social influence, they are unlikely to be featured in the media or receive concentrated criticism from many people, even if it is a crime. Doctors are responsible and have a public interest job. In addition, a medical license requires such noble and valuable work. For this reason, if you do something unethical, you may be subject to more bashing and severe criticism than you can imagine. Estheticians do not have national qualifications and are not a public-interest job. However, the work is actually wonderful, and I believe it is an important job that heals the body and mind and supports beauty. Esthetics is a job that is originally meant to provide healing, but some beauty salons have become a money-making tool, using illegal methods to attract customers, illegal activities, and illegal cosmetic sales methods to make a profit. Just as there are cosmetic surgery clinics backed by anti-social organizations, we cannot deny the possibility that there are beauty salons backed by anti-social organizations. The problems with both cosmetic surgery and beauty salons are exactly the same.・The owner lives a flashy lifestyle and behaves in a flashy manner (rich) ・Misuse of photos and names of celebrities (a scammer's tactic) ・Illegal activities (violation of the Medical Practitioners Act, the Pharmaceuticals and Medical Devices Act, and the Act against Unjustifiable Premiums and Misleading Representations) ・Profit comes first ・Exaggeration ・False PR and undignified advertising ・Methods that imply involvement of organizing organizations such as parties and ●● conventions ・Acts that pretend to be of public interest ・No academic basis ・Unfounded treatments and techniques ・Promotion of low prices ・Tie-ups with illegal and unscrupulous businesses There are ways to tell. If you find a cosmetic surgery clinic or beauty salon that fits the above criteria, it's best to steer clear. I hope there are no more illegal beauty salons or unscrupulous cosmetic surgery clinics in Nagoya!

Illegal beauty salon cosmetics and treatments?

Reading Time: <1 minuteThere is a case where an illegal beauty salon is selling illegal cosmetics in Nagoya.

With this content, one would think that this product would be a medicine. Why do they make exaggerated claims? It's to attract customers by touting medical effects. If they make exaggerated claims, naturally, clients are more likely to visit the beauty salon or purchase the cosmetics in hopes of seeing those effects. Since they are making illegal exaggerated claims for profit only, it goes without saying that the treatments at the salon and the cosmetics they sell are not trustworthy.

Expressions that cannot be used in cosmetic advertisements or packaging are regulated by the Pharmaceuticals and Medical Devices Act and the guidelines of the Fair Trade Commission because they may be misleading to consumers. Below are specific expressions that generally cannot be used in cosmetic advertisements or packaging:

Expressions suggesting therapeutic effects
- "Cure acne": Cosmetics are not intended for medical treatment but to improve skin condition, so expressions that suggest therapeutic effects cannot be used.
- "Remove blemishes": Statements guaranteeing the effectiveness of removing blemishes or freckles cannot be used as these products fall into the category of pharmaceutical products.
Hype
- "Completely" or "100% effective": Since the effectiveness of cosmetics varies from person to person, statements that guarantee absolute results should be avoided.
- "Miraculous" or "Dramatic": Exaggerated statements that have no scientific basis are not allowed.
Statement that guarantees safety
- "No side effects": This expression cannot be used because it cannot be said with certainty that there will be no side effects in everyone.
- "All natural" or "chemical-free": Even if a product is made entirely from natural ingredients, it should be used with caution as it may be misleading to consumers.
Representations that guarantee a particular effect
- "Immediate effect": Statements that guarantee short-term results should be avoided.
- "Permanent": No statements that guarantee permanent results may be used.
Pharmaceutical expressions
- "Antibacterial" or "sterilizing": These expressions are used for pharmaceuticals and cannot be applied to cosmetics.
- "Anti-inflammatory effect": Statements that guarantee an anti-inflammatory effect also fall under the category of medicines.

Illegal beauty salons ignore these prohibited expressions and advertise cosmetics. Because it is a minor offense, the police rarely crack down on it.

Surely there must be a huge number of victims who have been deceived by illegal advertisements and purchased these cosmetics only to find that they have no effect at all or that their acne has worsened?

Recently, medical-like expressions such as "containing stem cell components" and "containing exosomes" have begun to be used.

This is a way to indirectly hint at its effectiveness.

It is unlikely that non-pharmaceutical cosmetics will contain ingredients that are effective against inflammation, acne, blemishes, or wrinkles.

Even in Nagoya, where I practice, there are unscrupulous and illegal beauty salons that do whatever they want, and illegal businesses that brazenly advertise and still sell HIFU treatment equipment, which is a clear violation of the Medical Practitioners Act, on their websites.　SALANJEE | SALANJEE　There are companies that are illegal. I have introduced this company on my blog before, but they are still promoting HIFU equipment on their website, which is considered illegal to use and perform in beauty salons.

What they have in common is that they exaggerate the treatments, cosmetics, and equipment they offer, all of which may be illegal.

Energy Therapy? I have seen advertisements using the name "Energy Therapy?" to promote its effectiveness in treating lower back pain, stiff shoulders, insomnia, and eye fatigue, but aren't these completely illegal advertisements?

Is it OK for people without medical qualifications to advertise and provide these types of treatments?

I also think that the media that publishes this type of advertising is a problem.

There should be no treatments at beauty salons that are effective for headaches...

I don't know whether this leading organization is at fault or whether there are illegal beauty salons that are continuing to use these expressions despite the organization's instructions not to do so, but I would like the competent authorities to take strict measures and take strict measures against illegal activities that deceive consumers, so as to prevent victims from being created.

*If you have been victimized by an illegal beauty salon, please feel free to contact us.

As a doctor who practices cosmetic medicine, I hope that illegal beauty salons and illegal cosmetics will disappear.

Illegal beauty equipment sales companies and illegal beauty salons

Reading Time: <1 minuteI have pointed out before that there is a HIFU sales company in Nagoya that seems to be an illegal beauty device.　Salinger https://www.salanjee.jp/　 The person involved here is JapanEnergy Therapy AssociationThey formed an organization called "Therapeutic Massage Therapy" and worked to popularize the revolutionary treatment of passing a weak electric current from the hands to the living body. It is not a medical treatment, but as an approach to the autonomic nervous system, it may be possible to fully experience it if the therapist's skills were high. The treatment content and techniques are wonderful in their pursuit of the ultimate in healing, and I have given lectures and guidance on the autonomic nervous system myself. It is a wonderful technique that provides the healing that is the essence of esthetics. However, there are many related stores and　Cures insomnia, stiff shoulders, lower back pain, and paralysisなど　Violation of the Pharmaceuticals and Medical Devices Act and Medical Practitioners ActSince they often use expressions such as "I'm sorry," we have strongly warned them to stop, but they have not listened and have distanced themselves from us. We do not know whether their illegal activities were discovered or if an internal split occurred, but this organization has now disappeared. We do not know whether they followed in the footsteps of this organization or were deceived by members of this organization and began engaging in illegal activities, but they have repeatedly advertised and promoted their medical treatments under similar names (energy therapyThere is an illegal beauty salon that calls itself an academy and teaches treatments that may be illegal. Illegal beauty equipment? Sales company Saranghe　They are still advertising and selling HIFU equipment on their website, which is certainly a violation of the Medical Practitioners Act. If HIFU is performed by anyone other than a doctor, it is a violation of the Medical Practitioners Act. If you are deceived into buying this HIFU device and undergoing HIFU treatment at a beauty salon, you are completely out of luck.　energy therapyIt is possible that beauty salons are operating without knowing that they are illegal, claiming to be effective against these diseases. If so, these illegal beauty salons may also be victims of the illegal corporation Sarangé. Could it be that Sarangé is teaching them a treatment that could be illegal, with a similar name, energy therapy? HIFU at eyelash extension salons, performed by people without cosmetology licenses, and disease treatment at beauty salons are all problems. Illegal beauty salons and illegal beauty equipment sales companies are operating in the shadows of cosmetic medicine. Despite the fact that illegal activities are so widely published in town magazines and websites, there is no crackdown. Illegal beauty salons and illegal beauty equipment sales companies are making more and more profits through these unfair methods, and I think there are many victims behind the scenes. If you have been a victim, I recommend that you muster up the courage to consult the police in your jurisdiction. *I think that all treatments at beauty salons that claim to improve various diseases and have a therapeutic effect are criminal...