Acne image

Blot and freckles

What is a stain?

Melanin is not excreted and accumulated in the epidermis

Blot generation mechanism

Blots are areas of the skin that appear darker and darker than the skin color because melanin increases and accumulates in the epidermis of the skin.

When exposed to ultraviolet light, melanin melanocytes in the epidermis are activated, producing excessive melanin and changing the skin color.

This is “sunburn”. Normally, melanin is pushed into the keratin by the turnover of the epidermis and peels off with the plaque, so that melanin does not accumulate. Epidermal cells repeat “turnover (metabolism)” that is reborn into new cells in about 28 daily cycles. The cells in the basal layer divide and push up to the surface of the skin, and eventually peel off from the surface. Therefore, melanin produced by exposure to ultraviolet rays also finishes its role in the 28 daily cycle and peels off with old cells.

However, if UV damage accumulates over a long period of time, melanin will be overproduced and turnover will change with aging, and melanin will not be excreted and accumulated in the epidermis.

Skin is roughly divided into the outermost epidermis and the inner dermis. The epidermis is deeply involved in the stain. Melanocytes (pigment cells) in the bottom basal layer of the epidermis produce melanin. When ultraviolet light is applied to the skin, an enzyme called tyrosinase is activated and a pigment called melanin is produced in the melanocyte.

This melanin is delivered to keratinocytes to protect the cell nucleus from ultraviolet rays. Melanin is not really bad, it plays an important role in protecting the skin.

Why can I stain it?

For various reasons, melanin is overproduced and turnoverIf the cycle is prolonged and the metabolism is delayed, the melanin that should have fallen off will not be excreted from the epidermis, resulting in pigmentation = “stains”. Ultraviolet rays are the main cause of stains.

Exposure to UV radiation for many years can damage the skin (photoaging), reduce its ability to heal, and reduce its ability to excrete melanin. Irregular living, smoking and stress promote aging and increase active enzymes. Active enzymes stimulate melanocytes and cause overproduction of melanin.

Excessive irritation to the skin can also cause pigmentation. If the skin is rubbed strongly during makeup removal or face washing, melanin may be produced by the stimulation and pigmentation may occur.

In particular, melasma, a stain that is peculiar to women, is exacerbated by the irritation of the skin.

The same goes for acne. Acne often rubs the skin strongly and causes a spot-like mark of pigmentation after inflammation. Just hitting the hair can spread inflammation and cause pigmentation.

Metabolic action to keep the skin reborn and maintain a normal state. After the top keratinocytes of the epidermis are generated in the basal layer,28It is pushed up while changing into the stratum corneum over the day. As a stratum corneum, it is responsible for the skin barrier and moisturizing functions2After a week, it will become dirt and peel off. This is the reincarnation cycle of epidermal cells.

Acne image

About types of spots and dullness

By performing treatment according to the type of stain,
Effective treatment can be performed.

  • Senile pigment group
    It is a pigment spot seen after middle age. There is mild thickening of the epidermis and an increase in melanin pigment, but the cause is currently unknown. It is a symptom of photoaging and is considered to be greatly influenced by ultraviolet rays that were repeatedly taken on a daily basis.
  • Sunlight pigment group
    It is a general stain that can be caused by sunburn or aging.
  • Sparrow egg spot
    It is one of the pigment spots (stains) that can appear on the skin, and is commonly called freckle. Heredity is related, and is often seen in fair-skinned people. In the pigment spot, the pigment cells in the skin are enlarged and melanin is increasing.
  • Melasma
    Appears as light brown spots on the face. Symmetrically appear in almost the same shape and size, especially around the cheekbones and spread over a relatively wide area.

Blemish treatment


Improvement of spots and dullness

Beautiful skin toning

Prepare skin texture and peel at the same time


Recovers and restores smooth skin

Hypervitamin infusion

Suppresses the production of melanin and diminishes spots and pigmentation.

Beauty drip

Suppresses the production of melanin and diminishes spots and pigmentation.

Placenta injection

Blemish and dullness disappear, smooth skin

Drink sunscreen helio care

Protects skin from UV rays to prevent spots

External medicine

(Vitamin C derivatives, Vitamin A induction, etc.

Internal medicine

(Vitamin C, tranexamic acid)
 Take 1 mg or more daily.Insurance coverage

Contact Us

Sakae Clinic Photo

Insurance medical institution

Cosmetic surgery / dermatology / plastic surgery in Nagoya

Sakae Clinic

Nishiki, Naka-ku, Nagoya, Aichi Prefecture 3-5-21
Nishiki HOTEI Building 2F
Closed day: Wednesday, irregular holidays
Medical treatment: Complete reservation system
10: 00: 19: 00
TEL. 0120-566-680
TEL. 052-953-9676

1 minute walk from Hisaya-Odori Station on Subway Sakuradori Line / Meijo Line
4-minute walk from Sakae Station on the Higashiyama Line