Beauty research and development materials

Beauty research and development materials

98 The Japanese Society of Cosmetic Surgery Presentation

Recent knowledge and ideas of Fractional Laser treatment

Abstract

the purposeRecently, skin rejevination treatment, acne scar treatment, and trauma scar treatment using a fractional laser have been actively performed in Japan.
In conventional fractional laser treatment, it was necessary to consider down time compared to IPL treatment, but this time we aimed to shorten down time and improve the treatment effect, as well as to reduce the patient's postoperative pain. Then, combination treatment and postoperative care were introduced and examined.
methodFractional laser treatment system using Random Sprayed Beam System Immediately after treatment with Sellas Evo, we introduced BENEV, a formulation containing Growth Factor, and combined treatment with CryoElectrophoresis using Cryocell.
ResultNot only improved the effect of fractional laser treatment, but also shortened down time and reduced pain after treatment.
ConsiderationCombination therapy using BENEV GF Complex, a growth factor based on the wound treatment process and recent wound treatment theory, and postoperative care using CryoElectrophoresis shorten not only the therapeutic effect of fractional laser but also the down time to patients It is considered to be an excellent technique to reduce the burden.
This time, we fully understand the wound healing process in fractional laser treatment.

Abstruct

ObjectiveSkin rejuvenation and treatment for acne and trauma scars using fractional laser have recently become frequently used in Japan as elsewhere.
Fractional laser treatment has heretofore required greater consideration of downtime than intense pulsed light (IPL) treatment, but the authors implement and discuss combination therapy and postoperative care intended to shorten downtime and improve treatment effectiveness as well as reducing postoperative pain in the patient.
MethodTreatment using a Sellas EVO fractional laser treatment system using a random sprayed beam system was followed by combination therapy implementing a Benev product containing growth factor and cryoelectrophoresis using Cryocell.
Results: Not only was the effectiveness of fractional laser treatment improved, but downtime was shortened and postoperative pain was lessened.
FindingsCombination therapy implementing a Benev GF Complex serum that contains growth factor and postoperative care using cryoelectrophoresis, based on the course of wound treatment and in keeping with recent theory on wound treatment, appears to be excellent procedure that not only yields the treatment effectiveness of fractional laser, but also shortens downtime and alleviates patient burden.
In this instance, the authors obtained results showing promotion of highly efficient skin rejuvenation through use of a procedure and system of fractional laser treatment that give adequate consideration to the course of wound healing.

GF-Haircare_Complex

GF-Haircare Complex Technology

The GF-Haircare Complex is a revolutionary hair restorer developed by advanced stem cell technology by a team of BENEV chemists and scientific researchers from the University of California who have extensively investigated the anti-aging effects of growth factors.
The growth factor contained in the GF Haircare Complex was obtained from human fibroblast medium (filtered and conditioned), which was obtained from foreskin stem cells in the tissue bank attached to the University of California, Irvine. It is generated using a proven process.
Infant foreskin is the most abundant progenitor tissue. Once the cells are removed and placed in the medium, the process does not need to be repeated.
The process begins with removing stem cells from the foreskin. By putting the tissue in a medium that contains the nutrient environment necessary for growth, the cell is convinced that it is in the same environment as the skin, and is propagated like skin fibroblasts.

GF-Haircare Complex Technology

The challenge is to provide a concentrated medium that allows the cells to grow. BENEV's human fibroblast medium was created with patent-pending state-of-the-art technology.
The challenge in purifying the media was addressed by sucking up all types of cells using a special machine. A laser sends a beam from all directions to determine the viability of a cell and sort out the quality of the cell.
All proteins are charged proteins and have a specific molecular weight.
Cell viability is always maintained by limiting the number of times growth factor cells replicate. Cells can replicate up to 32 times before aging, but BENEV is limited to 16 times to maintain quality.

BENEV GF-Haircare Complex

GF-Haircare Complex works by promoting the health of the scalp and hair follicles. 40% of people who suffer from hair loss have lost their hair due to unhealthy scalp.
Growth factors have been proven to be good for the skin and at the same time have an effect on the scalp. Growth factors reach the hair follicles, stimulate repair, immune function, blood flow and growth, and lead to healthy scalp and hair.
If the hair follicle has already died, the GF-Haircare Complex cannot revive it, but it can stimulate stem cells under the scalp and promote the growth of new hair follicles.

BENEV Difference

Minoxidil, a vasodilator, works by increasing the blood supply to the hair follicle, but the problem is that this expensive treatment must last a lifetime. It takes 6 months to start seeing the results, and if you stop using it, your hair will begin to come off again and you will have to start over.
Finasteride (trade name Propecia) blocks the male hormone dihydrotestosterone (DHT), known for damaging hair follicles. However, every man can make DHT in his body, but not all men experience hair loss. There are many factors that can cause hair loss, but people with unhealthy scalp are more susceptible to DHT than those with healthy scalp. Finasteride also has many undesirable side effects: mood swings, rashes, impotence, loss of libido, etc.
BENEV GF-Haircare Complex has no side effects or dependence.

BENEV-GF-Press release

FOR IMMEDIATE RELEASE
May 2, 2017
Contact: Stephanie Smith
stephanie@BENEV.com(509) 685-0249
Restore Youthful Skin with Growth Factor Biotechnology

NEW Growth Factor Complex Serums from BENEV®
Mission Viejo, CA—BENEV® announces the release of three new skin serums based on the latest biotechnological research into the skin healing and anti-aging effects of growth factors: Growth Factor Rejuvenating Complex, Growth Factor Brightening Complex, and Growth Factor Body Care Complex.
These concentrated serums are designed to be used with electroporation, inotophoresis, and transepidermal delivery systems that include topical applications so that the complexes penetrate deeply into the skin for maximum interaction with skin cells.

Growth factors are natural proteins abundant in young, healthy skin that nourish skin cells and keep them active, regulating repair and renewal processes.They are involved in cell generation, collagen production, and elastin production.

These functions help keep skin taut, firm, and smooth.As skin ages or suffers photo-damage from sun exposure, it produces fewer growth factors, loses elasticity, and develops wrinkles and discoloration.
Now, advances in biotechnology have made it possible to produce growth factors in a laboratory and stabilize them for topical application.

BENEV® Growth Factor Complex serums all contain epidermal growth factor and fibroblast growth factor to replenish the skin's supply of these crucial proteins and fight visible signs of chronological and sun-induced aging. Epidermal growth factor helps encourage new skin cell generation, which slows down as skin ages, to replace dull, aging, wrinkled skin with a more youthful, smooth, radiant complexion.

Fibroblast growth factor helps to increase the production of fibroblasts, which synthesize collagen and elastin for firmer, more resilient, youthful skin. for visibly healthier skin.

Growth Factor Rejuvenating Complex is designed to diminish the appearance of fine lines and wrinkles, increase firmness and elasticity, and restore a youthful glow to skin.
• Growth Factor Brightening Complex is designed to treat pigmentation problems such as uneven skin tone, age spots, and sun spots with aminoethylphosphinic acid, which helps inhibit melanin production.
Growth Factor Body Care Complex is designed to diminish the appearance of stretch marks and increase skin firmness and tone.Includes green bean extract, methylsilanol hydroxyproline aspartate, and rutin to smooth stretch marks.

About BENEV Company, Inc.
BENEV is committed to serving medical skin care professionals around the world by developing scientifically advanced, effective solutions that promote optimum skin health.
All BENEV products are developed in our FDA-approved drug manufacturing facility with stringent quality control to ensure safety and efficacy.Available only through physicians.For more information, call 1-888-43-BENEV or go towww.BENEV.com.
For more information, please contact Stephanie Smith, BENEV marketing, at 509-685-0249, orStephanie@BENEV.com.
BENEV Company Inc.
23263 Madero, Suite A, Mission Viejo, CA 92691, USAwww.BENEV.com
949-457-2222, 949-457-2221, fax
Progressive Skin Science ™

Wound treatment in cosmetic surgery-Journal of the Japanese Society of Cosmetic Surgery

Methods of Wound Treatment in Cosmetic Surgery

Nobuhiro Suetake *, Yukiko Morita *, Sachiko Kaji **
* Sakae Clinic
** Juntendo University School of Medicine Hospital Administration
Nobuhiro Suetake, MD *, Yukiko Morita, MD *, Tomoko Kajisa, MD **
* Sakae Clinic
** Department of Hospital Administration, Juntendo University School of Medicine

Even in recent advances in cosmetic surgery, the importance of wound care for suture wounds and surgical wounds has been rarely discussed. Cosmetic surgeons are required to have more knowledge and techniques about wound care than general surgery. In recent years, many wound dressings have been used, but the basic usage and techniques related to wound care will be discussed.

Platelet rich plasma (PRP) is a plasma in which platelets are concentrated by centrifugation, and the biological activities of various cytokines and growth factors released from platelets, and the tissue adhesion and wound covering effects of fibrin and platelet glue. Therefore, clinical application from the aspects of regenerative treatment and wound healing is being attempted. This time we report that we applied PRP therapy to wound care in cosmetic surgery and obtained good results.

Key words: gauze dressing, sterilization, moist wound healing, platelet rich plasma, wound dressing


Introduction


While cosmetic surgery has made remarkable progress in recent years, the importance of wound care in suture wounds and surgical wounds has not been discussed much. It seems that traditional surgeons perform wound treatment using traditional disinfection and gauze, but it is necessary to maintain a moist environment to heal the wound. Wet dressing therapy using materials has become mainstream. Since cosmetic surgeons are required to have more knowledge and skills about wound care than general surgeons, it is necessary to master wound treatment.

This time, we reviewed the conventional wound treatment, approached the new wound, and obtained good results. Based on the basic wound healing theory, we will discuss recent wound treatment methods with specific techniques. introduce.



Main issue

1)Wound healing theory


The basics of wound treatment are the same whether it is a trauma, postoperative suture wound, or trouble treatment such as postoperative infection or necrosis. If the wound healing process is compared to cell culture, it is necessary to maintain the moist environment by placing the cells in the culture medium when culturing the cells. It can be seen that the tissue fluid that plays is important and the wound must not be dried.

It is desirable to maintain the wound in a closed and moist environment if no infection is observed in the trauma or postoperative suture wound. The tissue fluid contains many cytokines and cell growth factors that promote wound healing (Figure 1. Wet therapy). Applying gauze directly to the wound is an act that impedes the wound healing process, as well as drying the wound. Conventionally, the action of applying gauze and sophratur フ ラ to a suture wound has been carried out naturally in many surgical operations, but when considering the process of wound healing, these actions are not meaningless, rather than wound healing. Will be delayed. In addition, dry gauze adheres to the wound surface, which is harmful because it causes bleeding and pain to the patient each time treatment is performed.

Even if it is a wound, the healing method differs between a suture wound and a skin defect wound. A suture wound is a controlled wound and undergoes a primary healing process. Immediately after the suturing, platelets are activated, various cytokines are released, and neutrophils and macrophages migrate to the wound with hemostasis. Epithelialization occurs within 48 time, and capillary growth occurs after 72 time (Figure 2. Suture wound healing process). Furthermore, skin defect wounds take different healing processes depending on the depth of the wound. In shallow skin defect wounds, epithelialization occurs from both the hair follicle and the skin at the wound edge, so healing is fast, but in deep skin defect wounds, granulation is formed and epithelialization occurs from surrounding skin, so it takes time to heal .

2)Disinfection Merits and Demerits

The state where the wound is infected (infection) is different from the state where bacteria are present in the wound (colonization).

Even if the wound appears to be small, Infection needs to be treated immediately. However, even if the wound is extensive, if it is colonized, treatment for infection is unnecessary and it is not necessary to disinfect. Whether or not the wound is infected is judged by the presence or absence of so-called four signs of inflammation (redness, pain, local heat, and swelling). In many cases, exudates or yellow necrotic substances are attached to the wound, but no infection has occurred, and appropriate diagnosis is important.

In principle, disinfection of suture wounds and necrotic surgical wounds is unnecessary. In order to prevent wound infection, drainage and debridement, which remove the source of infection such as necrotic tissue from the wound surface, are more important. Disinfection does not remove the source of infection, and disinfection does not prevent infection.

Also, disinfectants do not selectively sterilize bacteria. When human cells and bacteria are compared, the bacteria are covered with a capsule and may be more resistant to disinfection than human cells. Then, even if the wound is disinfected, the bacteria are not killed, but only human cells are damaged, and wound healing is delayed.

Disinfectants are not always useful for living organisms. There have been reports of cases of anaphylactic shock caused by the use of chlorhexidine (Hibiten®, Hexac®), and povidone iodine (Isodyne®) also has a high rate of contact dermatitis.

In particular, cosmetic surgeons should recognize that there is a risk of disinfecting the wound, and disinfecting the surgical wound after surgery should properly understand and consider the advantages and disadvantages of disinfection. Do not routinely disinfect suture wounds. Reasonless disinfection only results in delayed suture wound healing and pain to the patient. There are cosmetic surgeons who perform extensive disinfection on surgical wounds before suturing, but infection can be caused by the tissue damage of disinfection. Wound disinfection does not effectively prevent infection or promote wound healing.



Case

1) Introducing a case of ACR (Autologus Cell Rejuvenation) therapy, which is an active wound therapy. 62, female. A case of burns after hair loss treatment for hemorrhoids. The patient himself used a commercially available disinfectant to dry the spray wound, causing infection and forming an ulcer with 4X × 7㎝ necrosis.

First, ACR therapy was performed after debridement of necrotic tissue. 16ml of autologous blood was collected, centrifuged at 3000 for 8 minutes, and platelet-rich plasma (PRP: Platelet Rich Plasma) was prepared using a Regen kit (Figure 7, 8. PRP actual). The prepared PRP 3cc was injected into the wound base and wound edge with a 33G needle and closed with a biocrucible wound dressing. 48 time closure therapy was performed, and the dressing was replaced on the third day after surgery. Thereafter, the wound contracted smoothly, and the wound was completely epithelialized on the 25 day after the operation.

During this time, bathing was performed as usual, and the wound surface was instructed to be washed thoroughly with shower every day after 3 days of treatment.

2) A case of suturing the incision of the upper eyelid. 26 years old, male. The stitched portion was covered with a cultist scissor that is an alginate coating material and covered with an opsite scissor that was a polyurethane film dressing. The next day's wound does not show crust formation, and the wound edges are completely consistent. On the day of suture 5, epithelialization was completed after removal of the thread.

3) Case of re-operation of labia plastic surgery performed in another hospital (Figure 10. Case 3). 33, female. A cultist scissors was placed on the sutured part after surgery. As a result, hemostasis from the wound becomes possible, and it immediately dissolves and the suture site becomes a moist environment. Patients were instructed to apply petrolatum to the wound every day to prevent drying. Bathing was possible from the next day, but there was no postoperative pain. After 1 weeks, the wound was completely epithelialized immediately after thread removal and no crust formation was observed.



Consideration

Platelet rich plasma (PRP) is a plasma in which platelets are concentrated by centrifugation, and the physiological activities of various cytokines and growth factors released from platelets, as well as the promotion of tissue adhesion and wound healing of fibrin and platelet glue. Expected to be effective. Platelets release various growth factors such as epidermal growth factor (EGF), transforming growth factor-beta (TGFβ), vascular endothelial growth factor (VEGF), and platelet-derived growth factor (PDGF) and many cytokines ( Figure 11.Network for wound healing). In PRP, platelets are concentrated about 2 to 6 times compared to peripheral blood, but leukocytes and various growth factors are also concentrated about 2 to 6 times, which may promote wound healing. Guessed. In addition to the physiological activity of platelet growth factor, PRP is expected to have hemostasis action by platelets, tissue adhesion action by fibrin / platelet glue, and skin scar suppression effect by anti-inflammatory effect. It is highly possible to apply. Previously, skin grafting had to be considered for the treatment of a wide range of skin necrosis such as case 1, but even with this PRP therapy, the wound was epithelialized and healed in a short period of time comparable to skin grafting. It becomes a treatment option. Similarly, the treatment of skin necrosis after surgery for armpit odors is not repeated sterilized or skin grafted, but if appropriate wound treatment is performed, there is almost no restriction on daily life for the patient and wound healing in a short period of time Is obtained.

Cultstat moth used in cases 2 and 3 is a wound dressing made of alginate extracted from seaweed kombu and made into a nonwoven fabric. Alginic acid absorbs moisture that is 15 to 20 times its own weight, and gels when it absorbs water containing sodium ions such as leachate. This gel functions to maintain a moist environment on the wound surface. It is characterized by having a very strong hemostatic effect by releasing calcium ions during gelation. From these facts, it can be said that this covering material is suitable for treatment of wounds with bleeding other than surgical wounds. Effective hemostasis and wound healing can be obtained even if the dressing is difficult to operate, such as in this case. For a wound wound care, only an alginate coating material and a film dressing material are sufficient, and no gauze or sophratur is required.

Cosmetic surgeons should be aware that there are major errors in traditional care methods such as disinfection of sutures, gauze, and bath restrictions. It is necessary not only to train surgical techniques but also to take care of suture wounds. The point of care for surgical wounds that we consider is to perform appropriate drainage and compression so as not to create hematoma or dead space. It is also important not to disinfect the wound before suturing the skin and not to apply gauze or sophratur s directly to the suture. Of course, the surgical wound after surgery is not disinfected, and after 48 time, the wound is washed and cleaned by bathing.

Recently, the thinking and methods related to wound treatment have changed completely, and there are many useful wound dressings, and it is necessary to become familiar with their usage. In the future, I hope that the correct wound treatment will become widespread and that more patients will benefit from it.

Methods of Wound Treatment in Cosmetic Surgery
English abstract (up to 200 words, 149 words)
Even with the remarkable strides made in cosmetic surgery in recent years, the importance of care for suture and surgical wounds has received little discussion.Cosmetic surgery requires greater knowledge and techniques for wound care than in general surgical procedures.Many wound-dressing materials have now come to be used; this discusses the fundamental usage methods and techniques of wound care.
Platelet-rich plasma (PRP) is an autologous concentration of platelets and growth factors, such as epidermal growth factor (EGF), transforming growth factor-beta (TGF-beta), vascular endothelial growth factor (VEGF), and platelet-derived growth Factor (PDGF). Increase of the wound repair rate by local application of a PRP solution has been reported.Its efficiency is proved in the domain of surgery, for treatment of severe burns and for the transplantation of cells and tissues.In this study, we applied this PRP treatment to wound healing in cosmetic surgery and great effectiveness was proven.



References


Akira Kuramoto. Dressing New wound management. Tokyo: Herus Publishing, 1995: 76-81.
Natsumi Natsui. Common sense insane of wound treatment. Declaration of disinfection and gauze eradication. Tokyo, 2004: 21-22.
Takahiko Moriguchi. TEXT plastic surgery. Tokyo: Nanzan Hall, 1995: 20-24.
Ichiro Ono. Wound treatment Recent progress. Tokyo: Katseido, 1993: 92-95.
Kirsner RS, Eaglstein WH. The wound healing process.Dermatol Clin 1993; 11: 629-40.
Field FK, Kerstein.Overview of wound healing in a moist environment.Am J Surg 1994; 167: 2S-6S.

Akihiro Mizuhara. PART 2 Wrap therapy practice that you want to know. Tokyo: Kanbara Publishing, 2005: 9-26.
Nobuo Kato. Medical microbiology 2nd edition. Tokyo: Asakura Shoten, 1997: 8-13.
Takashi Imazawa, Yuzo Komuro, Masahiro Inoue and others. A case of 1 who developed anaphylactic shock after using chlorhexidine gluconate. Nikkei journal 2003; 23: 582-588.
Takeshi Nakata. Contact dermatitis due to medical external medicine. Allergy clinical 2005; 25: 1086-1090.

Rozman P, Bolta Z. Use of platelet growth factors in treating wounds and soft-tissue injuries. Acta Dermatovenerol Alp Panonica Adriat 2007; 16: 156-65.
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Ichiro Ono. The role of cytokines in wound healing and its potential for clinical application. Plastic surgery 1998; 41: 909-916.
Eppley BL, Pietrzak WS, Blanton M. Platelet-rich plasma: a review of biology and applications in plastic surgery.Plast Reconstr Surg 2006; 118: 147e-159e.
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Yasuyuki Igarashi. How to use wound dressing. Derma. 2007; 132: 121-127.

Future and prospect of PRP therapy

Amazing regenerative medicine, PRP therapy-that medalist has revived!

As the only clinical research institute for PRP therapy for athletes in Japan, we are currently conducting research with Juntendo University School of Medicine.
The Japanese government and organizations that promote regenerative medicine are conducting research on regenerative medicine as "innovative medical technology aimed at the radical cure of degenerative diseases that were impossible until now by cell transplantation and tissue transplantation." It is defined as In other words, medical care to “regenerate” and rejuvenate a part of the body that has become unusable or aged. For example, instead of skin that has been damaged by burns, artificial skin or your skin is cultured. It is famous for the treatment of using bone marrow and the treatment of transplanting bone marrow to leukemia patients. In other words, it is a treatment that restores the function of your own cells, other people's cells, or other animal's cells by applying some ingenuity from the outside of the cells to exert their abilities in the body. .

Latest trends in regenerative medicine
The Ministry of Education, Culture, Sports, Science and Technology has lifted the ban on research to create germ cells from human ES cells, human ips cells, and human tissue stem cells. As a result, advanced research by Prof. Nakayama, Kyoto University, is progressing at each university and research institution. If germ cells can be created by differentiating human ES cells, germ cell maturation and differentiation mechanisms can be studied, leading to the elucidation of the causes of many diseases and the establishment of new diagnosis and treatment methods. The

Regenerative medicine and PRP
There is PRP injection therapy using its own platelets as a method of tissue regeneration and rejuvenation / wound treatment using autologous cells. PRP is an abbreviation for Platelet Rich Plasma, which is formally called platelet-rich plasma infusion therapy because it increases the concentration of your own platelets.


This treatment uses platelets taken from your own blood, so there is no rejection and there is no worry about virus infection. Application in the field of beauty such as tissue rejuvenation and wrinkle reduction by PRP injection therapy was first developed in Japan in 2006.
In Japan, beauty has a great clinical track record.
It is one of the cells contained in platelet blood. Blood consists of blood cells and plasma of liquid components. Blood cells include red blood cells, white blood cells, and platelets. Red blood cells survive about 120 days, but platelets are about 7 days. Platelets are 2μ in diameter and smaller than red blood cells and white blood cells, and the number is about 1% of the whole blood cells.

Platelets
1 has a hemostatic effect and 2 has a wound healing effect.

History of treatment using platelets

The treatment using platelets was started around 1990 led by Dr. Robert Marks, a surgeon at the University of Miami, USA. Dr. Marks wrote in his book, “From the beginning of the 1990 to the present day, the growth factors contained in platelets have the power of wound healing and are important cells that initiate wound healing in all humans. It was discovered. "

Why are platelets effective for wound healing and rejuvenation?

Platelets are characterized by internal storage grains, and storage granules consist of three types of granules (1ysosoma 1 granules, dense granules, alpha granules), and alpha granules store growth factors. Platelets are dormant (inactive) while circulating in the blood vessels, but activate when wounded, first promote clotting for hemostasis, and proliferate necessary for tissue repair to treat wounds Release factor.


The growth factors released from platelets include the following, each with its own role.

  1. Platelet-derived growth factor
  2. Transforming growth factor
  3. Vascular endothelial growth factor-VEGF
  4. Epithelial proliferating cells-EGF
  5. Fibroblast growth factor-FGF

PRP therapy and its mechanism

PRP therapy increases and accelerates the platelets' ability to heal wounds, repair and rejuvenate tissues. It creates a high concentration of platelets (PRP) and works to further promote wound healing. To do so, it is necessary to collect and activate high-concentration platelets.
There are various opinions about the plasma platelet count required for a large therapeutic effect, but it is said to be clinically effective at 4-7 times the normal platelet count.

Blood cells in human blood are usually about 1% platelets. PRP has a platelet concentration of about 94% to 96%, and the rest is a few red blood cells and white blood cells. The significance of using PRP is to increase the effect of growth factors that have a beneficial effect on healing by increasing the number of platelets.


How PRP works

The action of PRP depends on the growth factor released by alpha granules in platelets. The release of these growth factors begins in the course of the clotting reaction and begins within 10 minutes after the start of clotting. Over 95% of the growth factor synthesized at that time will be released within 1 hours.
Like most growth factors, growth factors in alpha granules in platelets require a certain process to work, and in that process become complete with biological activity.

PRP is produced using a centrifuge in a clean state, separating platelets from red blood cells and other components at high speed, and extracting them so as not to break or damage the platelets.

Practice and cases of PRP rejuvenation, wound treatment, and tissue damage applications

Skin rejuvenation treatment by PRP injection uses self cells, so this therapy is ACR therapy (Autologus Cell Rejuvenation,) which means rejuvenation by self cells.

ACR therapy (PRP injection therapy / platelet-rich therapy) is the 2 treatment that applies the effect of platelets to heal wounds, rejuvenating the entire skin and repairing damaged tissue. Moreover, it only uses about 20cc of its own blood and has no side effects or allergic reactions. The effect varies from person to person, but the skin condition improves over about 1 to 3 months, and the effect lasts for about 1-2 years.
In the treatment of chronic Achilles tendinitis, dramatic effects appear in about 2 weeks, and the effects last for more than half a year.

(PRP injection therapy / platelet-rich therapy)

* Improve wrinkles, sagging and texture
* Wound healing promotion (burn, flesh, fracture, ligament damage, Achilles tendinitis ...)
* Acne scars
* Skin rejuvenation
* Burns
* Skin trauma
* Skin necrosis
* Tennis elbow
* Golf elbow
* Meat separation
* Achilles tendon disorder
* Ligament injury
* Ganglion

Flow of PRP therapy


First, about 20cc of autologous blood is collected.
My Cells kit (My Cells kit) for creating PRP, which is very safe and good in performance, has been released from Israel, and it has become possible to safely perform PRP therapy even in clinics. The MyCell Kit is a very safe product that has only acquired the US FDA and European CE mark.
The collected blood is centrifuged and separated into a plasma part containing platelets and red blood cells by the action of a gel separator. A high concentration of platelets is gathered in about 1cm below the plasma, and this part is called PRP. Only this part is taken into a syringe and used for treatment.

In order for PRP to work effectively, the collected platelets are alive without being destroyed, and in order for platelets to work effectively and to regenerate the skin, it must be activated and release growth factors.
The injection method of PRP collected with the Mycell kit is injected into damaged tissue and skin with a very fine needle.

A case of PRP clinical injection effect by Mycel

Application of PRP to other areas

Safe and clinically effective PRP therapy using self-blood not only in the beauty field
Practical use in the field of orthopedics such as the dental field, arthritis, and tendonitis is already progressing mainly in the United States. In addition, it is expected that research and practical application will continue to become more active in the future, such as skin transplantation, burn treatment, and application to animal treatment.

In Japan, anti-aging treatments have been introduced into the beauty field and are widely used, but their effects vary greatly depending on the ability of the practitioner and the quality of the kit used. In 2009, we started clinical trials and research on athletes with PRP therapy, which is expected to become popular in the future from abundant PRP clinical cases and experience of athlete care at the sports department.
Carefully examined the course and effects, procedures, injection volume, injection site, and protocol, and in collaboration with Veritas Co., Ltd. Prof. Hiroyuki Kobayashi, Department of General Medicine, Juntendo University School of Medicine, Department of Orthopedic Surgery, Juntendo University School of Medicine The
Already overseas, top athletes active in the NBA, major leagues, Olympic gold medalists and others have introduced PRP therapy to take care of breakdowns.
Tiger Woods has also announced that he is officially treating Achilles tendon rupture and ligament injury with PRP therapy.
In our hospital, PRP therapy was performed for the first time in Japan to treat athletes with Achilles peritonitis for purposes other than cosmetic purposes.
Track & Field Men 110MH Athletes, Japan Olympics national representative and former Japanese record holder Masato Naito suffered from strong Achilles tendon pain before the Beijing Olympics and received PRP therapy for the Achilles tendon, which dramatically improved pain and the 2010 Japan Championships It became possible to participate in, and 5th place was won. Challenges for the London Olympics continue. There is a strong desire to continue PRP therapy not only for pain improvement but also for the fundamental treatment of Achilles tendon.
Introduced by Naito, he won two bronze medals for 400MH in the world, and Suedai also went to the Achilles tendon and patella ligament which failed PRP therapy.

An article about the revival race was published in the daily sports on the day of 4 month 11, and it was introduced that PRP therapy was treated in this article.

<Onshore: Recording session> ◇ 4 9th of May (Japan time 10th) ◇ Claremont, California, USA

 
The University of Suzhou (32 = a-meme) returned to the race for the first time in two years and eight months since the Beijing Olympics. Participated in a 400 meter run at a recording event hosted by the University of Panoma, California. The time was mediocre, 48 seconds 74, but he returned after overcoming the fight against injury. 侍 Hadler has returned to the front line.

Because I finished the run, the 1 facial expressions were filled with a pleasant sense of fulfillment. “This is the first time I have come to the stadium since Beijing. When things like scary started, time was not good, but I was really happy to race and finish.”

The breakdown continued after the Beijing Olympics. In particular, suffering from pain in the left knee, he received PRP treatment in which his own platelets were injected into the affected area last August. Originally a cosmetic surgery technique, and entrusted the life of athletes to the treatment that Tiger Woods and others received. The retirement crossed her head, saying, “If you can't do it this year, it ’s no good,” but the pain has completely disappeared in the last three months.

In the future, I will return to Japan and finally challenge the 400 meter obstacle at the Kanazawa record party on the 17th. Depending on the record, participation in Shizuoka International on the 3rd of next month will be decided. The goal for this season is to advance to the final of the World Championship in August. To get the right to participate, it is necessary to break the participation standard record (A standard 49 seconds 40, B standard 49 seconds 80) and advance to the Japanese championship in June. The big goal is to participate in the London Olympics next year. “I dreamed of fighting the finals of the Olympics. I was able to feel that dream today.” 侍 Take a big step from the land of the United States to revive Hadler.


Dramatic recovery from 3 months ago
2011.4.10 17:31
 He said he had to rest for 3 days because of pain after practicing once when he suffered from a breakdown. It was about 3 months ago when it turned to the best. He explained that he had received treatment to inject platelets into both knees and left Achilles tendon, "originally a cosmetic technique. It worked dramatically on Achilles tendon."

He will be 33 years old in May. I felt the decline with age, and said the running method, "The ability to sustain the dash fell the most. The concept that does not fly from the beginning, smoothly one round". (Joint)


[From 2011 year 4 month 11 day 9 hour 13 minute daily sports newspaper]

In addition, athletes representing Japan have been revived to the competition after receiving this treatment and feeling the effects of improving pain and range of motion.
It is expected to attract more and more attention in Japan as an innovative treatment that does not lead to doping.
In the future, PRP therapy may also be used for general injuries such as flesh, fractures, sprains, and fingertips.
We were able to expect a great therapeutic effect with burns and skin injuries, and in fact, we experienced a case where a remarkable effect was seen in our hospital as a treatment for intractable third degree burns.
Ganglion will also be used to care for wounds after surgery.
Regenerative medicine, which was thought to be a distant medicine, will soon become familiar.
Please stay tuned.

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Sakae Clinic Photo

Insurance medical institution

Cosmetic dermatology and cosmetic surgery in Nagoya

Sakae Clinic

〒460-0003
Nishiki, Naka-ku, Nagoya, Aichi Prefecture 3-5-21
Nishiki HOTEI Building 2F
Closed day: Wednesday, irregular holidays
Medical treatment: Complete reservation system
10: 00: 19: 00
TEL.0120-566-680
TEL.052-953-9676

1 minute walk from Hisaya-Odori Station on Subway Sakuradori Line / Meijo Line
4-minute walk from Sakae Station on the Higashiyama Line