Reading Time: <1 minuteDecember XNUMXnd Jikken Festival　https://jihiken-fes.jp/ At the lecture,[Beyond exosomes! ?Evidence and possibilities of vagus nerve activation therapy]I gave a lecture titled "Exosome therapy is attracting attention, but there have been reports of problems caused by injecting reagents that are not standardized and do not have guaranteed quality, with profits being prioritized. Vagus nerve stimulation therapy, which has solid evidence, guaranteed safety, and is thought to be as effective as or better than exosome therapy, will surely attract attention in the healthcare field in the future. On December 3rd, the president and directors of the Japan Society of Aesthetic Internal Medicine gathered on stage. A session was held. The Japan Society of Aesthetic Internal Medicine was founded, and we would like to work to popularize evidence-based aesthetic internal medicine therapy.