Reading Time: <1 minute On April 4st (Sunday), a commemorative lecture will be held to commemorate the inauguration of the Japanese Society of Aesthetic Internal Medicine, of which I am the director. Each director will give a talk session, and I am planning to talk about neuromodulation, or Vagal Treatment, as a next-generation medical treatment. Stimulation of the vagus nerve, which is the human operating system.This control is essential care for internal beauty and anti-aging. In the world, research on vagus nerve stimulation therapy, especially transcutaneous vagus nerve stimulation Yanagi method, is progressing, many papers have been released, and evidence is being established. Regenerative medicine has great potential and can become a big business, but it is still in its development stage. Transcutaneous Vagus Nerve Stimulation TVNS is an anti-aging medical treatment recognized by researchers around the world. Regarding Vagal Treatment, I am the representative director and president of the company, which conducts research and development.