Reading Time: <1 minuteThe topic at the social gathering after the lecture at the INFIX beauty community the day before yesterday was the information that a fatal accident occurred regarding stem cell culture supernatant and exosome infusion. The other day, I exchanged opinions on this topic with Dr. Akira Aoki, president of the Japan Society of Aesthetic Internal Medicine, a newly established association, and his secretary-general. The conclusion was that although it is convenient, certain medical procedures should be prioritized, and the society should strive not only to exchange academic information but also to disseminate correct medical information. Many specialists gathered and discussed, and came to the conclusion that it is necessary to carefully discuss the actual nature of the exosome business and stem cell culture supernatant business, which is currently in a lawless state. We are working to popularize vagus nerve activation therapy, which is expected to have the same or greater effect as exosomes and stem cell culture supernatant infusion. Vagus nerve activation therapy is a method of activating the vagus nerve, which controls most of the functions of the body, through training and treatments combined with devices and breathing techniques. Evidence has been established and safety has been confirmed by meta-analysis, so it will surely attract attention as a next-generation healthcare method. This lecture was attended by many directors of the Japanese Society of Aesthetic Internal Medicine at INFIX's Aesthetic Medicine Community. https://news.yahoo.co.jp/articles/fb51f3e64792fc987564fefcffd91b7c9b31f376 I would be happy if I could be of some help to the development of aesthetic medicine.